Serotype-specific protection against Treponema hyodysenteriae infection in ligated colonic loops of pigs recovered from swine dysentery.
نویسندگان
چکیده
Resistance to Treponema hyodysenteriae (serotypes 1, 2, 3, and 4) infection was evaluated in ligated colonic loops in pigs recovered from swine dysentery. Lesions were present in most loops from recovered swine inoculated with heterologous serotypes; however, lesions were not present in loops of recovered swine inoculated with homologous serotypes.
منابع مشابه
Pigs experimentally infected with Serpulina hyodysenteriae can be protected from developing swine dysentery by feeding them a highly digestible diet.
Weaner pigs (n = 72) were fed 1 of 4 diets. These were based on either cooked rice and animal protein, cooked rice and lupin, wheat and lupin, or wheat and animal protein. Twenty-six of the pigs were slaughtered after 1 month. Those fed the highly digestible cooked rice and animal protein diet had drier colonic contents and faeces, lighter large intestines, and the contents of their large intes...
متن کاملSelective medium for isolation of Treponema hyodysenteriae.
Pure cultures of six pathogenic isolates of Treponema hyodysenteriae, the colonic mucosal scrapings of seven pigs with acute swine dysentery, and feces from seven unaffected pigs were diluted in phosphate-buffered saline and plated on Trypticase soy agar with 5% citrated bovine blood (TSA) and TSA with various levels of spectinomycin (TSA-S). The plates were incubated at 42 degrees C in a vente...
متن کاملExperimental infection with Treponema hyodysenteriae in guinea pigs.
Outbred and inbred (Hartley strain) guinea pigs (GP) were inoculated intragastrically with pathogenic and nonpathogenic Treponema hyodysenteriae. GP 3 to 16 weeks old received T. hyodysenteriae after a fasting period of 36 to 72 h. Infected GP with pathogenic T. hyodysenteriae developed a diarrheal and/or depressive condition, with mucus but not blood in the feces. Of 88 GP, 40 had gross lesion...
متن کاملAn avirulent Brachyspira hyodysenteriae strain elicits intestinal IgA and slows down spread of swine dysentery
Swine dysentery caused by Brachyspira hyodysenteriae, results in substantial economic losses in swine producing countries worldwide. Although a number of different vaccine approaches have been explored with regard to this disease, they show limitations and none of them have reached the market. We here determine the vaccine potential of a weakly haemolytic B. hyodysenteriae strain. The virulence...
متن کاملHyperimmune gnotobiotic pig serum raised against purified axial filaments of strain P 18A (serotype 4) cross-reacted with all other serotypes and with the non-pathogens, and convalescent serum taken from a pig with persistent swine dysentery
Purified axial filaments from eight serotypes of Treponema hyodysenteriae and two nonpathogenic intestinal spirochaetes were characterized by SDS-PAGE and Western blotting. Axial filaments of all ten strains had similar SDS-PAGE profiles; five major axial filament polypeptides were identified, with molecular masses of 43.8, 38, 34.8, 32.8 and 29.4 kDa. Hyperimmune gnotobiotic pig serum raised a...
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عنوان ژورنال:
- Infection and immunity
دوره 39 1 شماره
صفحات -
تاریخ انتشار 1983